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TBI Clinical Results: Vielight itPBM Boosts Neuromuscular Health

This article is based on independent TBI research conducted with the Vielight Neuro Gamma by the University of Utah

Vielight Neuro Gamma

Educational summary of published clinical research on intranasal-transcranial photobiomodulation (itPBM) using Vielight technology in individuals with a history of repetitive head acceleration events (RHAEs) and related cognitive concerns. The Vielight Neuro is categorized as a general wellness device by the FDA. It is not cleared or approved by the U.S. FDA to diagnose, treat, cure, mitigate, prevent, or manage traumatic brain injury (TBI).

In the world of high-impact sports, “getting your bell rung” has long been dismissed as part of the game. However, we now know that repetitive head acceleration events (RHAEs), even those that don’t result in a clinical concussion, can lead to long-term declines in motor control, balance, and reaction time.

A groundbreaking n=43 clinical study from the University of Utah, utilizing Vielight Neuro (itPBM) technology, suggests a new way for athletes to fight back.

FULL STUDY LINK

“Football almost killed me… But Vielight saved my life.” — Dr. Larry Carr, PhD Kinesiology.

The Athlete’s Challenge: Hidden Impact

Athletes in contact sports may experience over 100 RHAEs per season. While often asymptomatic, these impacts cause microstructural changes in the brain similar to a mild Traumatic Brain Injury (mTBI). Over time, this “cumulative burden” can dampen motor unit recruitment, slow down reaction speeds, and impair the dynamic balance required for elite performance.

The study focused on individuals with a history of repetitive impacts, emphasizing the long-term cumulative burden of sports:

  • Total Enrolled: 49 participants.

  • Study Completion: 43 participants (39 male, 4 female).

  • Age Range: 18–69 years old (mean age 49.5).

  • Condition: Self-reported history of concussions or RHAEs from recreational, collegiate, or professional sports.

  • Adherence: High user engagement with a 92% compliance rate over the 8-week period.

Clinical Performance Tests

Four assessments were conducted alongside cognitive and neuropsychological tests and a brain MRI:

  • Clinical Reaction Time
    Participants caught a falling stick with their dominant hand to measure reaction time, calculated using the distance the stick dropped and the formula for a body falling under gravity.
  • Grooved Pegboard Test
    Manipulative dexterity was assessed using a metal board with 25 keyhole-shaped slots. Participants inserted pegs into the holes as quickly as possible, recording the time taken to complete the task with each hand.
  • Grip Strength
    Measured using a Jamar Plus Dynamometer, participants squeezed the handle as hard as possible for 3 seconds, with three trials per hand. The average force was recorded.
  • Mini Balance Evaluation Systems Test (MiniBEST)
    This test assessed 14 tasks across four domains (anticipatory postural adjustments, reactive postural control, sensory orientation, and dynamic gait), scoring each task on a three-level ordinal scale with a maximum total score of 28. The overall score and individual subscores for each domain were recorded.

Key Performance Wins

After 8 weeks of using the Vielight Neuro Gamma, participants showed statistically significant improvements in areas vital for competition:

  • Faster Reactions: Average reaction time improved by 19.39 ms.

  • Increased Power: Dominant hand grip strength grew by 2.70 kg, and non-dominant strength by 3.73 kg.

  • Better Stability: Balance scores (MiniBEST) improved significantly, particularly in reactive postural control.

 


 

The Study: Boosting Neuromuscular Health

The University of Utah researchers investigated how 8 weeks of itPBM treatment using the Vielight Neuro Gamma influenced the neuromuscular health of individuals with a history of RHAEs. The results highlight significant gains in three critical athletic domains:

  1. Explosive Reaction Time: Participants saw a significant improvement in reaction speed, averaging a 19.39 ms faster response. In sports where milliseconds separate a win from a loss, this is a massive advantage.

  2. Grip Strength (Bilateral): The study recorded increased grip strength in both the dominant (2.70 kg increase) and non-dominant (3.73 kg increase) hands.

  3. Dynamic Balance & Reactive Control: Using the MiniBEST assessment, researchers found moderate improvements in reactive postural control. This suggests a better ability to recover from sudden shifts in balance—essential for avoiding further injury on the field.

 


 

Test Result Improvement Significance
Reaction Time

-19.39 ms (Faster)

p < 0.001

 

Non-Dominant Grip

+3.73 kg (Stronger)

p < 0.001

 

Dominant Grip

+2.70 kg (Stronger)

p = 0.003

 

Balance (MiniBEST)

+1.32 Points (Stable)

p < 0.001

 

How it Works: The itPBM Advantage and "Mitochondrial Fueling"

While standard tPBM therapy helmets often struggle to penetrate the thick barrier of the human skull, the Vielight Neuro Gamma utilizes a patented dual-delivery system known as itPBM. This approach combines high-power transcranial stimulation with a unique intranasal gateway to ensure photons reach the brain’s most critical “power hubs”.

1. High-Irradiance Vie-LED Technology

Unlike off-the-shelf LEDs found in consumer-grade helmets, Vie-LEDs are custom-engineered modules designed for “laser-like” energy delivery. They provide industry-leading irradiance (the concentration of light energy), which is essential for deep tissue penetration.

  • Targeted Delivery: The headset positions these powerful LEDs directly over the nodes of the Default Mode Network (DMN)—the brain’s primary communication highway—including the medial prefrontal cortex and the precuneus.

  • Precision Optics: Each Vie-LED module uses secondary optics to focus light, ensuring that the photons actually reach the neural tissue rather than scattering at the scalp.

2. The Intranasal Gateway

The “i” in itPBM stands for intranasal, a patented Vielight advantage that allows light to bypass the cranium entirely.

  • Bypassing the Skull: By utilizing the cribriform plate (a porous bone at the roof of the nasal cavity), the intranasal probe delivers 810nm light directly to the underside of the brain and the olfactory bulbs.

  • Systemic Boost: This channel also irradiates the dense capillary network in the nasal mucosa, potentially offering a systemic benefit by stimulating blood cells as they circulate.

3. Fueling the Brain: 810nm & ATP

The technology specifically utilizes the 810nm near-infrared wavelength, which is the “sweet spot” for mitochondrial absorption.

  • The CCO Trigger: These photons are absorbed by cytochrome c oxidase (CCO), a key enzyme in the mitochondria.

  • Performance Gains: This triggers a biological cascade that increases ATP (cellular energy) production, enhances cerebral blood flow, and reduces the chronic neuro-inflammation often seen in athletes with a history of head impacts.

References

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This article was written by

Dr. Genane Loheswaran

Vielight | Research Manager and Neuroscientist

Genane manages Vielight’s research projects with various organizations for cognitive science, such as combining photobiomodulation with EEG.

MSc in Neuroscience, McMaster University
PhD in Pharmacology, University of Toronto
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