Published Research with Vielight technology

20+
Published studies with Vielight technology
3
continents (research sites)
17+
Ongoing studies and clinical trials
15+
Published studies with Vielight technology
3
continents (research sites)
13+
Ongoing studies and clinical trials

We are grateful to the many bright minds we’ve had the honor of collaborating with globally over the years to advance the field of photobiomodulation research.

Condition | TopicInstitutionVielight DeviceResearch TypeStatus
  • Dementia

Published Study

University of California San Francisco | US Veterans AffairsVielight Neuro GammaClinical StudyCompleted
  • Dementia

Published Study

Harvard Medical School | Boston University School of MedicineVielight Neuro GammaClinical StudyCompleted
  • Alzheimer’s Disease

Clinical Trial Information

Unity Health, TorontoVielight Neuro GammaClinical StudyAnalysis Stage
  • Alzheimer’s Disease

Clinical Trial Information

University of Florida | University of Arizona | National Institute on AgingVielight 810 [MIP]Phase 2 Clinical Trial (n=168)Ongoing
  • Alzheimer’s Disease

Clinical Trial Information

St Michael’s Hospital | Vielight IncVielight Neuro GammaPhase 3 Clinical Trial
(n=228)
Ongoing
  • Alzheimer’s Disease

Clinical Trial Information 

University of California San Francisco | US Veterans AffairsVielight Neuro GammaClinical StudyResults Analysis
  • Traumatic Brain Injury (TBI)

Published Abstract 

Researchers and Participants Documentary

Department of Neurology, University of UtahVielight Neuro GammaClinical Trial (n=49)Pre-publication
  • Traumatic Brain Injury (CTE)

Published Study

Boston University School of Medicine | Harvard Medical SchoolVielight Neuro GammaClinical StudyCompleted
  • Traumatic Brain Injury (CTE)

Published Study

Researchers and Participants Documentary

Department of Neurology, University of UtahVielight Neuro GammaClinical Trial (n=43)Completed
  • Traumatic Brain Injury (TBI)

Published Study

VA Advanced Imaging Research Center, San Francisco VA Health Care SystemVielight Neuro GammaClinical StudyCompleted
  • Traumatic Brain Injury (TBI)

Clinical Trial Information 

Boston Veterans Affairs Research InstituteVielight Neuro GammaClinical StudyOngoing
  • Parkinson’s Disease

Published Study

University of SydneyVielight Neuro GammaClinical StudyCompleted
  • Parkinson’s Disease

Clinical Trial Information

University of FloridaVielight 810 [MIP]Phase 2 Clinical trial (n=135)Ongoing
  • Parkinson’s Disease

Clinical Trial Information 

University of Sydney | University of BrisbaneVielight Neuro GammaClinical StudyRegistered
  • PTSD | Gulf War Illness

Published Study

University of California San Francisco | US Veterans AffairsVielight Neuro AlphaClinical Study Completed
  • Autism Spectrum Disorder (ASD)

Published Study

Neurodevelopment Division, Istituto di Neuroscienze, ItalyVielight Neuro DuoClinical Study Completed
  • Covid-19 Recovery

Pre-print of Results

Medical Device License

Vielight IncVielight RX PlusPivotal Phase 3 Clinical Trial (n=295)Completed
  • Neuromodulation (Gamma 40Hz)

Published Study

University of Toronto | Vielight IncVielight Neuro GammaClinical StudyCompleted
  • Neuromodulation (Alpha 10Hz)

Published Abstract

Vielight IncVielight Neuro AlphaClinical StudyPre- Publication
  • Microtubulin Photobiomodulation

Published Study

Princeton University | University of Alberta | Vielight IncVielight Neuro AlphaResearch StudyCompleted
  • COVID-19 Respiratory Symptoms

Pre-print of Results

Medical Device License

Vielight IncVielight RX PlusPivotal Phase 3 Clinical Trial (n=295)Completed
  • Antimicrobial Photodynamic Inactivation

Published Study Link

Harvard Medical SchoolVielight Blue [MIP]Scientific Study Completed
  • Antimicrobial Blue Light Therapy for Infectious Keratitis

Published Study Link

Harvard Medical SchoolVielight Blue [MIP]Scientific Study Completed
  • Antimicrobial blue light inactivation of Candida albicans

Published Study Link

Harvard Medical SchoolVielight Blue [MIP]Scientific StudyCompleted
  • Enhancement of Divergent Creative Thinking

Published Study Link

University of Deusto, Spain | University of Montpellier, France | Pennsylvania State UniversityVielight Neuro GammaClinical Research (n=56) Completed
  • Spectroscopy Photobiomodulation and Tubulins: Implications for Alzheimer’s

Published Study Link

University of Alberta | Polytechnic University of TurinVielight Neuro AlphaScientific StudyCompleted

  • Alzheimer’s Disease (Dementia)

Effects of Home Photobiomodulation Treatments on Cognitive and Behavioral Function and Resting-State Functional Connectivity in Patients with Dementia: A Pilot Trial
Institutes – University of California San Francisco & the Veterans Affairs USA

[ Simplified Summary | Device: Vielight Neuro Gamma | Published Study ]

Significant Improvement in Cognition in Mild to Moderately Severe Dementia Cases Treated with Transcranial Plus Intranasal Photobiomodulation: Case Series Report
Co-authoring institutes – Harvard Medical School, Boston University School of Medicine

[ Published Study | Device: Vielight Neuro Gamma ]

Vielight Neuro RX Gamma – Alzheimer’s Disease Pivotal Phase III Clinical Trial (n=228)
Co-institutes – St Michael’s Hospital, Toronto

[ Clinical Trial Information Link ] (228 participants | 3 years | Ongoing)

Neuro RX Gamma for Amnestic Mild Cognitive Impairment (aMCI) / Dementia
Co-institutes – Unity Health Toronto, Toronto

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ]

Revitalizing Cognition in Older Adults at Risk for Alzheimer’s Disease With Near-Infrared Photobiomodulation

Institutes – University of Florida, University of Arizona, National Institute on Aging (NIA)

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ] (168 participants | 5 years | Registration)

Impact of Photobiomodulation (PBM) on Biomarkers of Alzheimer’s Disease
Institutes – University of California San Francisco UCSF

[ Clinical Trial Information Link / Device: Vielight Neuro Gamma ] (16 participants | 1.5 years | Ongoing)

  • Traumatic Brain Injury / Concussion

The Effect of Intranasal Plus Transcranial Photobiomodulation on Neuromuscular Control in Individuals with Repetitive Head Acceleration Events (n=43)
Institutes – Department of Neurology, University of Utah

[ Simplified SummaryPublished Study | Device: Vielight Neuro Gamma ] (43 participants)

Transcranial Photobiomodulation Treatment Effects In Former Athletes With Repetitive Head Hits (n=49)
Institutes – Department of Neurology, University of Utah

[ Published Abstract Link | Device: Vielight Neuro Gamma ] (49 participants | Pending publication)

Transcranial Photobiomodulation Treatment: Significant Improvements in Four Ex-Football Players with Possible Chronic Traumatic Encephalopathy
Institutes – Boston University School of Medicine, Harvard Medical School

[ Published Study Link | Device: Vielight Neuro Gamma ]

The Effect of Intranasal Plus Transcranial Photobiomodulation on Neuromuscular Control in Individuals with Repetitive Head Acceleration Events
Institutes – Institutes – Department of Neurology, University of Utah

[ Published Abstract Link | Device: Vielight Neuro Gamma ]

Changes in Brain Function and Structure After Self-Administered Home Photobiomodulation Treatment in a Concussion Case
Institutes – VA Advanced Imaging Research Center, San Francisco VA Health Care System, Departments of Radiology & Biomedical Imaging and Psychiatry & Behavioral Sciences, University of California, San Francisco

[ Published Study Link | Device: Vielight Neuro Gamma ]

Traumatic Brain Injury Recovery with Photobiomodulation: Cellular Mechanisms, Clinical Evidence, and Future Potential
Institutes – Vielight Inc

[ Published Study Link ]

Photobiomodulation to Improve Cognition in TBI, With fMRI
Institutes – Boston Veterans Affairs Research Institute

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ] (20 participants | 1 years | Ongoing)

  • Parkinson’s Disease

Improvements in clinical signs of Parkinson’s disease using photobiomodulation: A prospective proof-of-concept study
Institutes – University of Sydney, University of New South Wales, Griffith University

[ Simplified Summary | Device: Vielight Neuro GammaPublished Study Link ]

Pilot Intervention With Near Infrared Stimulation
Institutes – University of Florida

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ] (135 participants | 4 years | Ongoing)

Evaluation of dose of Photobiomodulation (Light) Therapy and Physiotherapy for Improving Quality of Life Outcomes and Mobility in Parkinson’s Disease (Pilot)
Institutes – University of Sydney, University of Brisbane

[ Clinical Trial Information Link | Device: Vielight Neuro Gamma ] (16 participants | 1.5 years | Ongoing)

  • PTSD and Gulf War Illness

Improvements in Gulf War Illness Symptoms After Near-Infrared Transcranial and Intranasal Photobiomodulation: Two Case Reports
Institutes – University of California San Francisco & the Veterans Affairs USA

[ Published Study Link | Device: Vielight Neuro Alpha ]

  • Autism Spectrum Disorder (ASD)

Transcranial Photobiomodulation for the Treatment of Children with Autism Spectrum Disorder (ASD): A Retrospective Study
Institutes – Neurodevelopment Division, Istituto di Neuroscienze, Italy, Department of Psychiatry, Albert Einstein College of Medicine, NY

[ Simplified Summary | Device: Vielight Neuro Duo | Published Study Link ]

  • Viral Recovery

Vielight RX Plus for Viral Infection Recovery

Health Canada Medical License Indication
“The Vielight RX Plus is intended to accelerate the recovery of upper respiratory symptoms in viral infections, such as COVID-19.” 

[ Results ] (295 participants ) | [ Medical Device License ]

  • Post-Covid

A Pilot Study Evaluating the Efficacy of the Vielight Neuro RX Gamma in the Treatment of Post COVID-19 Cognitive Impairment
Various clinical sites

[ Clinical Trial Information ] (36 participants | 1 year | Recruitment)

  • Cognitive Enhancement and EEG-Neuromodulation

Enhancement of Divergent Creative Thinking After Transcranial Near-Infrared Photobiomodulation Over the Default Mode Network
Institutes – University of Deusto | University of Montpellier | Pennsylvania State University

[ Published Study Link | Summary | Device: Vielight Neuro Gamma ]

Pulsed Near Infrared Transcranial and Intranasal Photobiomodulation Significantly Modulates Neural Oscillations: a pilot exploratory study
Institutes – Centre for Therapeutic Brain Intervention, Centre for Addiction and Mental Health, Toronto, Ontario, Canada

[ Published Study Link (Nature, Scientific Reports, 2019) | Device: Vielight Neuro Gamma ]

Modulation of cortical oscillations using 10hz near-infrared transcranial and intranasal photobiomodulation: a randomized sham-controlled crossover study

[ Abstract Text Link | Device: Vielight Neuro Alpha ]

  • Bioenergetics and Cellular Enhancement

Near-Infrared Photobiomodulation of Living Cells, Tubulin, and Microtubules In Vitro
Institutes – Department of Physics and the Department of Chemistry, University of Alberta | Scholes Lab, Department of Chemistry, Princeton University, Princeton, NJ, United States | Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Turin, Italy | Vielight Inc

[ Published Study Link | Device: Vielight Neuro Alpha ]

Raman Spectroscopy Reveals Photobiomodulation-Induced α-Helix to β-Sheet Transition in Tubulins: Potential Implications for Alzheimer’s and Other Neurodegenerative Diseases
Institutes – University of Alberta, Polytechnic University of Turin, Freie Universit¨at Berlin, Silesian University of Technology

[ Published Study | Device: Vielight Neuro Alpha ]

  • Systemic, Anti-Viral and Anti-Microbial

Vielight RX Plus for the Treatment of COVID-19 Respiratory Symptoms
Various clinical sites

[ Pre-print of Results ] (295 participants | 1 year | Pre-publication)

[ Medical Device License ]

Antimicrobial Photodynamic Inactivation Mediated by Tetracyclines in Vitro and in Vivo: Photochemical Mechanisms and Potentiation by Potassium Iodide
Institutes – Harvard Medical School

[ Published Study Link | Vielight MIP ]

Antimicrobial Blue Light Therapy for Infectious Keratitis: Ex Vivo and In Vivo Studies
Institutes – Harvard Medical School

[ Published Study LinkVielight MIP ]

Antimicrobial blue light inactivation of Candida albicansIn vitro and in vivo studies
Institutes – Harvard Medical School

[ Published Study Link | Vielight MIP ]

Location

Research Affiliation

Disclaimer: The published research links are independent information sources about photobiomodulation. No representation is made regarding Vielight devices or their capabilities.

Brain (transcranial) Photobiomodulation (tPBM)

Penetration

Transcranial photobiomodulation : simulation of dosimetry
Harvard Psychiatry Department, Harvard Medical School : Link ]

Red and NIR light dosimetry in the human deep brain
Institute of Chemical Sciences and Engineering, Switzerland : Link 1 | Link 2 ]

Photon Penetration Depth in Human Brains
The University of Southern California : Link ]

Monte Carlo analysis of the enhanced transcranial penetration using distributed near-infrared emitter array.
Institute of Biomedical Engineering, Chinese Academy of Medical Science : Link ]

Transcranial Red and Near Infrared Light Penetration in Cadavers
State University of New York Downstate Medical Center : Link ]

Cellular Effects

Photobiomodulation Directly Benefits Primary Neurons Functionally Inactivated by Toxins
Medical College of Wisconsin : [ Link ]

Neuroprotective effects of photobiomodulation : Evidence from assembly/disassembly of the Cytoskeleton
University of Sydney : [ Link ]

Photobiomodulation – mitochondrial ROS generation and calcium increase in neuronal synapses.
Lin-Kou Medical Center, Taiwan : [ Link ]

Infrared neural stimulation and functional recruitment of the peripheral Nerve
Department of Biomedical Engineering, Case Western Reserve University : [ Link ]

Cognition

Effect of Transcranial Low-Level Light Therapy vs Sham Therapy Among Patients With Moderate Traumatic Brain Injury
Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston : [ Link ]

Brain Photobiomodulation Therapy: a Narrative Review
Department of Medical Physics, Tabriz University of Medical Sciences : [ Link ]

Psychological benefits with near infrared light to the forehead: a pilot study on depression
The Department of Psychiatry, Harvard Medical School and the Laboratory for Psychiatric Biostatistics, McLean Hospital : [ Link ]

Cognitive Enhancement by Transcranial Photobiomodulation Is Associated With Cerebrovascular Oxygenation of the Prefrontal Cortex
Department of Psychology, Institute for Neuroscience, University of Texas : [ Link ]

Mitochondrial Dysfunction-Near-Infrared Photobiomodulation as a Potential Therapeutic Strategy
Department of Research, National Neuroscience Institute, Singapore : [ Link ]

Transcranial Photobiomodulation For The Management Of Depression: Current Perspectives
Department of Psychiatry, NYU Langone School of Medicine, New York, NY, USA : [ Link ]

Increased Functional Connectivity Within Intrinsic Neural Networks in Chronic Stroke Following Treatment With Red/Near-Infrared Transcranial Photobiomodulation
Boston University School of Medicine, Harvard Medical School : [ Link ]

Review of transcranial photobiomodulation for major depressive disorder: targeting brain metabolism, inflammation, oxidative stress, and neurogenesis
Wellman Center for Photomedicine, Massachusetts General Hospital : [ Link ]

Shining light on the head : Photobiomodulation for brain disorders
Wellman Center for Photomedicine, Massachusetts General Hospital : [ Link ]

Improved cognitive function after transcranial, light-emitting diode treatments in chronic, traumatic brain injury: two case reports
Boston University, School of Medicine : [ Link ]

Augmentation of cognitive brain functions with transcranial lasers
Department of Psychology and Institute for Neuroscience, University of Texas : Link ]

Neurological and psychological applications of transcranial lasers and LEDs
Department of Neurology and Neurotherapeutics, University of Texas : Link ]

Novel Methods

A novel method of applying NIR light intracranially, impact on dopaminergic cell survival
University of Sydney, CEA-Leti : [ Link ]

Low Level Systemic (via blood) Photobiomodulation

General research

Blood contains circulating cell-free respiratory competent mitochondria
Université de Montpellier : [ Link ]

Interplay between up-regulation of cytochrome-c-oxidase and hemoglobin oxygenation induced by near-infrared laser
University of Austin at Texas : [ Link ]

Red/Near Infrared Light Stimulates Release of an Endothelium Dependent Vasodilator and Rescues Vascular Dysfunction
US Veterans Affairs : [ Link ]

Low-Level Light Therapy Protects Red Blood Cells Against Oxidative Stress and Hemolysis During Extracorporeal Circulation
Regional Specialist Hospital, Poland : Link ]

How Photons Modulate Wound Healing via the Immune System
King’s College London (KCL), University of London : [ Link ]

Randomized, Double-Blind, and Placebo-Controlled Clinic Report of Intranasal Low-Intensity Laser Therapy on Vascular Diseases
Ministry of Education, Key Laboratory of Laser Life Science, China : [ Link ]

Blood Laser Irradiation : current state and future perspectives
ABER Institute, Helsinki, Finland : [ Link ]

Intravenous Laser Blood Irradiation
MH Weber : [ Link ]

Applications of Intranasal Low Intensity Laser Therapy In Sports Medicine
Journal of Innovative Optical Health Sciences, World Scientific : [ Link ]

Formation of gigantic mitochondria in human blood lymphocytes under the effect of a low level laser source
Institute on Laser and Informatic Technologies of Russian Acad. : [ Link ]

Irradiation with He-Ne laser increases ATP level in cells cultivated in vitro
National Cancer Research Centre of the Academy of Medicine and Science : [ Link ]

Photobiomodulation Mechanisms

Photobiomodulation—Underlying Mechanism and Clinical Applications : [ Link ]

Therapeutic Photobiomodulation: Nitric Oxide and a Novel Function of Mitochondrial Cytochrome C Oxidase : [ Link ]

Mechanisms of Low Level Light Therapy : [ Link ]

Basic Photomedicine : [ Link ]

The Nuts and Bolts of Low Level Light Therapy : [ Link ]

Disclaimer: Some of the research information pertains to ongoing clinical trials. No representation is made regarding Vielight devices or their capabilities beyond published results.

Please note that the Neuro Gamma device is not the same as the Neuro RX Gamma that is currently being used in our clinical trials.
The RX Gamma is intended to be fully compliant with regulatory requirements for a medical device and will not be available without regulatory clearance. The “Neuro RX Gamma” is therefore a different product from the “Neuro Gamma”.