Photobiomodulation

Learn about the science behind Vielight devices, why irradiance and wavelengths matter, and what makes photobiomodulation therapy so effective for your brain.

How photobiomodulation therapy boosts your brain's potential

Near-infrared (NIR) energy penetrates the skull

The NIR energy reaches brain cells

Mitochondria absorb NIR energy, boosting cellular energy and brain function

Photobiomodulation benefits

Increases the production of Adenosine Triphosphate (ATP)

A molecule that fuels nearly all biological activity, including cellular growth and repair.

Promotes the release of
 Nitric Oxide (NO)

A molecule that enhances cellular signaling and improves blood circulation.

Generates low levels of Reactive Oxygen Species (ROS)

Mild oxidants that trigger gene transcription for cellular repair and healing.

What is photobiomodulation?

Photobiomodulation (PBM), often referred to as light therapy, is a non-invasive treatment that uses near-infrared (NIR) light to enhance cellular health and performance.

This light is delivered through specialized LEDs and directed at targeted areas of the body to stimulate biological responses. With the appropriate wavelength and sufficient irradiance, PBM can reach deep tissue depths to support different therapeutic goals.

At its core, PBM helps cells produce more ATP—the energy molecule essential for all cellular activity. With increased energy, cells are better equipped for repair, regeneration, and maintenance, which can lead to improved recovery and overall well-being.

Vielight Skull NIR Penetration Demo

Wavelength x Irradiance

What is wavelength and irradiance?

In photobiomodulation, the concentration of light energy (irradiance) is vital besides wavelength. A systematic review of over 2000+ PBM studies found the average parameters for effective therapy were 810nm and 250 mW/cm².

Vielight’s Vie-LED technology delivers high-intensity, laser-like energy, surpassing the weaker irradiance of helmet-style devices.

Even with hundreds of LEDs, helmets dilute power by sharing electrical current across many diodes. This weak irradiance prevents deep penetration, reducing effectiveness.

Vielight Neuro

Energy Footprint Comparison on
a real human skull

Vielight Neuro

The Science Behind Vielight

What makes PBM effective?

For photobiomodulation to be effective, three key factors must align: the correct wavelength (typically 633–810 nm) to ensure proper absorption; the right intensity to avoid underdosing or overheating tissue; and an adequate energy dose to achieve results.

These principles are guided by the foundational laws of photobiology, which state that without absorption, no biological reaction can occur, and that dose and intensity must work together to be effective.

What is photobiology?

Photobiology studies how non-ionizing light affects living systems, with different wavelengths producing different biological effects. Light is absorbed by molecules like DNA or proteins, triggering chemical changes and cellular responses.

Examples include vitamin D production from sunlight and vision, both driven by light-induced biochemical reactions. These interactions show how light continues to play a vital role in energizing biological processes.

What is brain photobiomodulation?

The brain, our most complex organ, relies on mitochondria in each cell as energy-producing “batteries.”

Photobiomodulation improves mitochondrial performance. This boost in cellular energy helps heal brain cells, repair neuron connectivity, and improve brain efficiency, ultimately enhancing overall brain function.

Near-infrared light, especially at 810 nm, penetrates deepest into brain tissue. To fine-tune photobiomodulation parameters for optimal results, research that uses Vielight technology employs brain imaging and brain signaling techniques.

See brain wellness devices More on NIR light

Brain Imaging Research

Diffusion Tensor Imaging (DTI) presentation

Why the nose?

From the inventor and neuroscientists

Biggest PBM clinical trial

n=294 clinical trial for Accelerated Viral Recovery

What is the Vielight Neuro 4?

See Neuro Duo 4

Published research with Vielight technology

Explore peer-reviewed studies featuring Vielight technology in collaboration with world-class institutions.

Alzheimer’s (Dementia)

Mild Cognitive Impairment

Brain Fog

PTSD

Traumatic Brain Injury

Viral Immunity

Neuromodulation

Cellular Enhancement

Parkinson’s

Autism

Cognitive Enhancement

Upper Respiratory Viral Recovery

In collaboration with

Real-world Vielight photobiomodulation breakthroughs

VIECLINIC Launch
Psychiatry Brain Intervention Center

Enhancing mental health with Vielight technology

VIECLINIC is a cutting-edge brain intervention clinic owned by Vielight, in collaboration with leading psychiatrists and neurologists. By integrating neurotechnologies, such as brain photobiomodulation, rTMS, tDCS with traditional pharmaceuticals, VIECLINIC and Vielight technology enhance traditional therapies, promoting recovery and long-term mental well-being. You can also incorporate Vielight devices into your own practice for similar benefits.

Learn more

TBI Photobiomodulation Clinical Trial Results
Researcher Interviews | U of Utah | Vielight Neuro

Accelerating traumatic brain injury recovery

At Vielight, we’ve made significant advances in traumatic brain injury research with our devices, such as the Neuro. Our studies show that these treatments effectively improve brain function, cognition, mood, reaction time, and physical strength in individuals with mild TBI, repetitive head impacts, and chronic conditions like traumatic encephalopathy. By incorporating our devices into your practice, you can offer your patients a non-invasive, evidence-based treatment that enhances brain connectivity, reduces symptoms, and accelerates recovery.

See studies

Parkinsons PBM Clinical Results

[Vielight Neuro Gamma / Irradia MID 2.5]

Transforming neurodegenerative treatment

At Vielight, we’ve made significant advances in Alzheimer’s and Parkinson’s research. Our transcranial and intranasal devices have shown to improve cognition, reduce symptoms, and enhance brain wellness by boosting connectivity, promoting neurogenesis. By incorporating our devices into your practice, you can offer patients a non-invasive, evidence-based treatment to support memory, motor function, and overall brain wellness in those managing these neurodegenerative conditions.

See studies

See research

Vielight Improves Brain Resilience: Published Brain Imaging Research | Football

Vielight Improves Brain Resilience: Published Brain Imaging Research | Football

Photobiomodulation

How photobiomodulation therapy boosts your brain's potential